南通市肿瘤医院生物治疗中心副主任
中国医药生物技术协会医药生物技术临床应用专业委员会委员
江苏省免疫学会青年工作委员会委员
江苏省第四期“333”中青年科学技术带头人
第一批“江苏省卫生拔尖人才”
江苏省转化医学研究院、南京医科大学转化医学研究院第三方评价平台、转化和培训平台特聘教授、专利评估专家

临床医学/免疫学

1、2015年获南通市九三学社先进个人荣誉称号
2、2017年获南通市五一劳动奖章
3、江苏省第四期“333”中青年科学技术带头人
4、第一批江苏“卫生拔尖人才”
5、2016年第二届南通市职工技术创新成果奖“十佳科技创新成果”

[1] Wu S*, He X*, Li M*, Shi F, Wu D, Pan M, Guo M, Zhang R, Luo S, Gu N, Dou J. MiRNA-34a overe­xpression inhibits multiple myeloma cancer stem cell growth in mice by suppressing TGIF2. Am J Transl Res. 2016 Dec 15;8(12):5433-5443. (*共同第一作者). 影响因子:3.146 (SCI)
[2] Dou J*, Ni Y*, He X*, Wu D, Li M, Wu S, Zhang R, Guo M, Zhao F. Decreasing lncRNA HOTAIR e­xpression inhibits human colorectal cancer stem cells. Am J Transl Res. 2016 Jan 15;8(1):98-108. (*共同第一作者). 影响因子: 3.402(SCI)
[3] Shi F*, Yang F*, He X*, Zhang Y, Wu S, Li M, Zhang Y, Di W, Dou J, Gu N. Inhibitory effect of epirubicin-loaded lipid microbubbles with conjugated anti-ABCG2 antibody combined with therapeutic ultrasound on multiple myeloma cancer stem cells. J Drug Target. 2016 Jan;24(1):34-46. (*共同第一作者).影响因子: 2.741(SCI)2.821
[4] Zhao F*, He X*, Wang Y*, Shi F, Wu D, Pan M, Li M, Wu S, Wang X, Dou J. Decrease of ZEB1 e­xpression inhibits the B16F10 cancer stem-like properties. Biosci Trends. 2015;9(5):325-34. (*共同第一作者). 影响因子: 1.663(SCI)
[5] Zhao F*, He X*, Sun J*, Wu D, Pan M, Li M, Wu S, Zhang R, Yan C, Dou J. Cancer stem cell vaccine expressing ESAT-6-gpi and IL-21 inhibits melanoma growth and metastases. Am J Transl Res. 2015 Oct 15;7(10):1870-82. (*共同第一作者). 影响因子: 3.402(SCI)
[6] Wang X*, Zhao F*, He X*, Wang J, Zhang Y, Zhang H, Ni Y, Sun J, Wang X, Dou J. Combining TGF-β1 knockdown and miR200c administration to optimize antitumor efficacy of B16F10/GPI-IL-21 vaccine. Oncotarget. 2015 May 20; 6(14):12493-504. (*共同第一作者).影响因子: 6.359(SCI)
[7] Wang J*, Chen D*, He X*, Zhang Y, Shi F, Wu D, Chen J, Zhang Y, Zhao F, Dou J. Downregulated lincRNA HOTAIR e­xpression in ovarian cancer stem cells decreases its tumorgeniesis and metastasis by inhibiting epithelial-mesenchymal transition. Cancer Cell Int. 2015 Feb 25;15:24. doi: 10.1186/s12935-015-0174-4. (*共同第一作者).影响因子: 2.766(SCI)原1.989
[8] Wang X*, He X*, Zhao F*, Wang J, Zhang H, Shi F, Zhang Y, Cai K, Dou J. Regulation gene e­xpression of miR200c and ZEB1 positively enhances effect of tumor vaccine B16F10/GPI-IL-21 on inhibition of melanoma growth and metastasis. J Transl Med. 2014 Mar 14;12:68. (*共同第一作者).影响因子: 3.991(SCI)
[9] Yang C*, He X*, Song L*, Zhan X, Zhang Y, Dou J, Gu N. γ-Fe2O3 Nanoparticles Increase Therapeutic Efficacy of Combination with Paclitaxel and Anti-ABCG2 Monoclonal Antibody on Multiple Myeloma Cancer Stem Cells in Mouse Model. J Biomed Nanotechnol. 2014 Feb;10(2):336-344. (*共同第一作者). 影响因子: 7.578(SCI)
[10] Dou J*, He X*, Liu Y*, Wang Y, Zhao F, Wang X, Chen D, Shi F, Wang J. Effect of downregulation of ZEB1 on vimentin e­xpression, tumor migration and tumorigenicity of melanoma B16F10 cells and CSCs. Cell Biol Int. 2014 Apr;38(4):452-61. (*共同第一作者). 影响因子:1.635(SCI)
[11] He X, Wang J, Zhao F, Chen D, Chen J, Zhang H, Yang C, Liu Y, Dou J. ESAT-6-gpi DNA vaccine augmented the specific antitumor efficacy induced by the tumor vaccine B16F10-ESAT-6-gpi/IL-21 in a mouse model. Scand J Immunol. 2013 Jul;78(1):69-78. 影响因子:1.882(SCI)
[12] Dou J*, He XF*, Liu Y*, Huang Z, Yang C, Shi F, Chen D, Gu N. Targeted therapeutic effect of anti-ABCG2 antibody combined with nano silver and vincristine on mouse myeloma cancer stem cells. J Nanopart Res. 2013 Dec;15(12):1-12.(*共同第一作者). 影响因子：2.287(SCI)
[13] Dou J*, He XF*, Cao WH*, Zhao FS, Wang XY, Liu YR, Wang J. Overe­xpression of microRna-200c IN CD44+CD133+ CSCS inhibits the cellular migratory and invasion as well as tumorigenicity in mice. Cell Mol Biol (Noisy-le-grand). 2013 Oct 13;Suppl 59:OL1861-8(*共同第一作者).影响因子：0.691(SCI)
[14] He X, Wang J, Zhao F, Yu F, Chen D, Cai K, Yang C, Chen J, Dou J. Anti-tumor Efficacy of Viable Tumor Vaccine Modified by Heterogenetic ESAT-6 Antigen and Cytokine IL-21 in Melanomatous Mouse. Immunol Res. 2012 Jun;52(3):240-249. 影响因子：2.963(SCI)
[15] Hu W*, Wang J*, He X*, Zhang H, Yu F, Jiang L, Chen D, Chen J, Dou J. Human umbilical blood mononuclear cell-derived mesenchymal stem cells serve as interleukin-21 gene delivery vehicles for epithelial ovarian cancer therapy in nude mice. Biotechnol Appl Biochem. 2011 Nov; 58(6):397-404. (*共同第一作者) 影响因子：1.534(SCI)